MOTS-c

MOTS-c
A naturally occurring mitochondrial-derived peptide composed of 16 amino acids, encoded within the Mitochondrial Open Reading Frame of the 12S rRNA type-c. Unlike most peptides produced from nuclear DNA, MOTS-c originates from mitochondrial DNA, where it helps regulate energy metabolism and cellular adaptation to stress.

Research Focus

• Regulation of cellular energy balance and metabolic signaling.

• Influence on glucose and fatty acid utilization for energy production.

• Activation of pathways that support metabolic homeostasis under stress.

• Study of mitochondrial-to-nuclear communication mechanisms.

• Investigation into exercise signaling and age-related metabolic changes.

Mechanisms Under Study

• Modulation of AMPK and related energy-sensing pathways.

• Coordination of mitochondrial signaling during oxidative or physical stress.

• Cellular adaptation to metabolic demand and nutrient availability.

Product Information

• Supplied as a lyophilized sterile powder.

• Third-party verified for purity, molecular identity, and composition.

• For laboratory research use only, not for human or animal use.